The “Problem”
The ageing of the human population globally has (among others) resulted in a significant increase of the so called non-communicable (or age-related) diseases and consequently in the need for novel treatments to enhance healthy ageing. It is also now apparent that the molecular-cellular basis of ageing and of all age-related diseases (e.g., cancer or neurodegeneration) is complex as for instance chronological age (referring solely to the passage of time) rarely matches biological age (indicates decline in function).